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2,4,6,8-Nonatetraenoicacid, 9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-, ethyl ester,(2E,4E,6E,8E)- (54350-48-0)

Identification
Name:2,4,6,8-Nonatetraenoicacid, 9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-, ethyl ester,(2E,4E,6E,8E)-
Synonyms:2,4,6,8-Nonatetraenoicacid, 9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-, ethyl ester, (all-E)-;Ethylall-trans-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoate;Ethyl etrinoate;Etretinate;Ro 10-9359;Tegison;Tigason;Tigasone;
CAS:54350-48-0
EINECS: 259-119-3
Molecular Formula: C23H30O3
Molecular Weight: 354.49
InChI: InChI=1/C23H30O3/c1-8-26-23(24)14-17(3)11-9-10-16(2)12-13-21-18(4)15-22(25-7)20(6)19(21)5/h9-15H,8H2,1-7H3/b11-9+,13-12+,16-10+,17-14+
Molecular Structure: (C23H30O3) 2,4,6,8-Nonatetraenoicacid, 9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-, ethyl ester, (all-E)-...
Properties
Melting Point: 104-1050C
Flash Point: 219.4°C
Boiling Point: 506.4°C at 760 mmHg
Density:1.006g/cm3
Refractive index:1.544
Appearance:Crystalline solid
Specification:

 Etretinate ,its cas register number is 54350-48-0. It also can be called Tigason ; Tigazon ; (all-E)-9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic Acid Ethyl Ester and Ethyl etrinoate . It is highly lipophilic and is stored in adipose tissue explaining why its effects can been felt for long periods of time following taking the drug, and has been replaced by acitretin, a metabolite of etretinate. Etretinate (CAS NO.54350-48-0) is a teratogen, and may cause birth defects long after use.

Report:

EPA Genetic Toxicology Program.

Flash Point: 219.4°C
Color: Crystals
Usage:Aromatic analog of Retinoic Acid. Immunomodulator. Antipsoriatic
Safety Data
 

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