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D-Mannitol,1,6-bis[(2-chloroethyl)amino]-1,6-dideoxy-, dihydrochloride (9CI) (551-74-6)

Identification
Name:D-Mannitol,1,6-bis[(2-chloroethyl)amino]-1,6-dideoxy-, dihydrochloride (9CI)
Synonyms:Mannitol,1,6-bis[(2-chloroethyl)amino]-1,6-dideoxy-, dihydrochloride, D- (8CI);1,6-Bis(chloroethylamino)-1,6-dideoxy-D-mannitol dihydrochloride; 1,6-Bis(b-chlorethylamino)-1,6-didesoxy-D-mannitoldihydrochloride; 1,6-Bis[(2-chloroethyl)amino]-1,6-dideoxy-D-mannitoldihydrochloride; Degranol; Degranol chinoin; Dimesylmannitol hydrochloride;Mannitol mustard dihydrochloride; Mannomustine dihydrochloride; Mannomustinehydrochloride; NSC 9698
CAS:551-74-6
Molecular Formula: C10H22 Cl2 N2 O4 . 2 Cl H
Molecular Weight: 378.13
InChI: InChI=1S/C10H22Cl2N2O4.ClH/c11-1-3-13-5-7(15)9(17)10(18)8(16)6-14-4-2-12;/h7-10,13-18H,1-6H2;1H
Molecular Structure: (C10H22Cl2N2O4.2ClH) Mannitol,1,6-bis[(2-chloroethyl)amino]-1,6-dideoxy-, dihydrochloride, D- (8CI);1,6-Bis(chloroethylam...
Properties
Specification:

 Mannomustine dihydrochloride , its cas register number is 551-74-6. It also can be called 1,6-Bis(beta-chloroethylamino)-1,6-dideoxy-D-mannitol dihydrochloride ; 1,6-Bis(chloroethylamino)-1,6-desoxymannitol dihydrochloride ; 1,6-Dideoxy-1,6-di(2-chloroethylamino)-D-mannitol dihydrochloride ; Degranol ; and Degranol chinoin . Its classification code are Drug / Therapeutic Agent; Mutation data; Reproductive Effect and Tumor data.

Report:

IARC Cancer Review: Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 ,1987,p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Sufficient Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 9 ,1975,p. 157.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) .

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