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Imidazo[1,2-a]pyridine-3-carboxylicacid (6200-60-8)

Identification
Name:Imidazo[1,2-a]pyridine-3-carboxylicacid
Synonyms:NSC 305198;NSC 305199;
CAS:6200-60-8
Molecular Formula: C8H6N2O2
Molecular Weight: 162.1454
InChI: InChI=1/C19H21F3N2O3S/c1-13(2)14-7-9-16(10-8-14)23-18(25)12-24(28(3,26)27)17-6-4-5-15(11-17)19(20,21)22/h4-11,13H,12H2,1-3H3,(H,23,25)
Molecular Structure: (C8H6N2O2) NSC 305198;NSC 305199;
Properties
Density:1.41 g/cm3
Refractive index:1.564
Appearance:Off white Solid
Specification:

The Imidazo[1,2-a]pyridine-3-carboxylic acid ,its cas register number is 6200-60-8.The IPUAC name about this chemicals is Imidazo[1,2-a]pyridine-3-carboxylic acid .Following are the physical and chemical properties about it: (1)#H bond acceptors: 4 ;(2)#H bond donors: 1 ;(3)#Freely Rotating Bonds: 1 ;(4)Index of Refraction: 1.676 ;(5)Molar Refractivity: 43.02 cm3 ;(6)Molar Volume: 114.3 cm3 ;(7)Surface Tension: 60.5 dyne/cm .It belongs to the following product categories, such as Carboxylic Acids, Carboxylic Acids and Fused Ring Systems.

The Imidazo[1,2-a]pyridine-3-carboxylic acid is a irriant chemicals, the hazard note also is Irritant. It is a off white solid.

This chemicals can be described computed from structure:
(1)Canonical SMILES: C1=CC2=NC=C(N2C=C1)C(=O)O
(2)InChI: InChI=1S/C8H6N2O2/c11-8(12)6-5-9-7-3-1-2-4-10(6)7/h1-5H,(H,11,12)
(3)InChIKey: DOGXPDFZEQXZDS-UHFFFAOYSA-N

The most important thing about Imidazo[1,2-a]pyridine-3-carboxylic acid is the toxicity, following is the form:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 2gm/kg (2000mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)		 Journal of Medicinal Chemistry. Vol. 12, Pg. 122, 1969.

Safety Data
Hazard Symbols Xi: Irritant
 

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