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Azelastine hydrochloride (79307-93-0)

Identification
Name:Azelastine hydrochloride
Synonyms:1(2H)-Phthalazinone,4-[(4-chlorophenyl)methyl]-2-(hexahydro-1-methyl-1H-azepin-4-yl)-,monohydrochloride (9CI);A 5610;Allergodil;Astelin;Astepro;Azeptin;E 0659;Optivar;Rhinolast;W 2979M;
CAS:79307-93-0
EINECS: 200-306-6
Molecular Formula: C22H24ClN3O.HCl
Molecular Weight: 418.3594
InChI: InChI=1S/C22H24ClN3O.ClH/c1-25-13-4-5-18(12-14-25)26-22(27)20-7-3-2-6-19(20)21(24-26)15-16-8-10-17(23)11-9-16;/h2-3,6-11,18H,4-5,12-15H2,1H3;1H
Molecular Structure: (C22H24ClN3O.HCl) 1(2H)-Phthalazinone,4-[(4-chlorophenyl)methyl]-2-(hexahydro-1-methyl-1H-azepin-4-yl)-,monohydrochlor...
Properties
Density:1.25 g/cm3
Stability:Incompatible with strong oxidizing agents.
Appearance:white crystalline powder
Specification:

Side effects of azelastine nasal spray vary somewhat depending on the condition being treated. The most common side effects include bitter taste, headache, rhinitis, nose bleed, and somnolence. Adults being treated for vasomotor rhinitis may also experience dysesthesia and sinusitis. Additional side effects experienced by adults being treated for seasonal allergies include nasal burning, pharyngitis, dry mouth, paroxysmal sneezing, nausea, fatigue, dizziness, and weight gain. Additional side effect can include a slight mind alertness.

Usage:

Orally active H1-hystamine receptor antagonist. Antihistaminic

Safety Data