| Identification | |
| Name: | Pravastatin sodium |
| Synonyms: | Mevalotin;Pravachol;Pravachol (TN);Pravastatine [French];1-Naphthaleneheptanoic acid,1,2,6,7,8,8a-hexahydro-a,?,6-trihydroxy- 2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-,monosodium salt,(aR,?R,1S,2S,6S,8S,8aR)-;Pravastatina [Spanish];Pravastatinum [Latin];1-Naphthaleneheptanoic acid, 1,2,6,7,8,8a-hexahydro-beta,delta,6-trihydroxy-2-methyl-8-(2-methyl-1-oxobutoxy)-, (1S-(1alpha(betas*,deltas*),2alpha,6alpha,8beta(R*),8aalpha))-;sodium (3R,5R)-7-[(1S,2R,6S,8S,8aR)-6-hydroxy-2-methyl-8-[(2S)-2-methylbutanoyl]oxy-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxy-heptanoate;1-Naphthaleneheptanoic acid, 1,2,6,7,8,8a-hexahydro-beta,delta,6-trihydroxy-2-methyl-8-((2S)-2-methyl-1-oxobutoxy)-, (betaR,deltaR,1S,2S,6S,8S,8aR)-;Lipostat;SQ 31000;Paravastatin; |
| CAS: | 81131-70-6 |
| Molecular Formula: | C23H35NaO7 |
| Molecular Weight: | 446.50957 |
| InChI: | InChI=1S/C23H36O7.Na/c1-4-13(2)23(29)30-20-11-17(25)9-15-6-5-14(3)19(22(15)20)8-7-16(24)10-18(26)12-21(27)28;/h5-6,9,13-14,16-20,22,24-26H,4,7-8,10-12H2,1-3H3,(H,27,28);/q;+1/p-1/t13-,14-,16+,17+,18+,19-,20-,22-;/m0./s1 |
| Molecular Structure: | ![(C23H35NaO7) Mevalotin;Pravachol;Pravachol (TN);Pravastatine [French];1-Naphthaleneheptanoic acid,1,2,6,7,8,8a-he...](https://img.guidechem.com/casimg/81131-70-6.gif) |
| Properties | |
| Transport: | 3077 |
| Flash Point: | 213.2 ºC |
| Boiling Point: | 634.5ºCat 760 mmHg |
| Water Solubility: | H2O: 19 mg/mL in water |
| Solubility: | H2O: 19 mg/mL in water |
| Appearance: | White Crystalline Powder |
| Specification: |
? Pravastatin sodium (CAS NO.81131-70-6), its Synonyms are 3-beta-Hydroxycompactin sodium salt ; Aplactin ; Bristacol ; Pravachol ; Pravacol ; Pravaselect ; Pravasin ; Pravasine ; Pravastatin Natrium Mayrho Fer ; Sanaprav ; Selektine ; Selipran ; Sodium (+)-(betaR,deltaR,1S,2S,6S,8S,8aR)-1,2,6,7,8,8a-hexahydro-beta,delta,6,8-tetrahydroxy-2-methyl-1-naphthaleneheptanoate, 8-((2S)-2-methylbutyrate) . |
| Packinggroup: | III |
| Biological Activity: | Water-soluble, competitive inhibitor of 3-hydroxy-3-methyl coenzyme A (HMG-CoA) reductase. Potently blocks cholesterol synthesis in vivo (K i ~ 1 nM) and displays cardioprotective properties. |
| Flash Point: | 213.2 ºC |
| Color: | white |
| Usage: | Pravastatin sodium (CAS NO.81131-70-6) can be used as a competitive inhibitor of HMG-CoA reductase, Bioactive metabolite of Mevastatin |
| Safety Data | |
| Hazard Symbols |
F: Flammable
C: Corrosive
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