| Identification |
| Name: | 1,2-Ethanediamine,N1,N2-bis(diphenylmethyl)- |
| Synonyms: | 1,2-Ethanediamine,N,N'-bis(diphenylmethyl)- (9CI);N,N'-Bis(diphenylmethyl)ethylenediamine; |
| CAS: | 83027-13-8 |
| Molecular Formula: | C28H30Cl2N2 |
| Molecular Weight: | 465.4572 |
| InChI: | InChI=1/C28H28N2.2ClH/c1-5-13-23(14-6-1)27(24-15-7-2-8-16-24)29-21-22-30-28(25-17-9-3-10-18-25)26-19-11-4-12-20-26;;/h1-20,27-30H,21-22H2;2*1H |
| Molecular Structure: |
 |
| Properties |
| Flash Point: | 321.5°C |
| Boiling Point: | 533.7°C at 760 mmHg |
| Biological Activity: | The first selective mGlu 7 agonist. Potently inhibits cAMP accumulation and stimulates GTP γ S binding in recombinant cells and on membranes expressing mGlu 7 (EC 50 = 64-290 nM). Selective over other mGluR subtypes and selected ionotropic glutamate receptors up to 10 μ M. Acts via a novel allosteric site and is orally active and brain penetrant. Reduces haloperidol-induced catalepsy in rats. |
| Flash Point: | 321.5°C |
| Safety Data |
| |
 |
