| Identification |
| Name: | 5H-Thiazolo[3,2-a]pyrimidin-5-one,6-[2-[4-[(4-fluorophenyl)phenylmethylene]-1-piperidinyl]ethyl]-7-methyl- |
| Synonyms: | DKGI-I;Diacylglycerol kinase inhibitor I; R 59-022 |
| CAS: | 93076-89-2 |
| Molecular Formula: | C27H26 F N3 O S |
| Molecular Weight: | 459.58 |
| InChI: | InChI=1/C27H26FN3OS/c1-19-24(26(32)31-17-18-33-27(31)29-19)13-16-30-14-11-22(12-15-30)25(20-5-3-2-4-6-20)21-7-9-23(28)10-8-21/h2-10,17-18H,11-16H2,1H3 |
| Molecular Structure: |
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| Properties |
| Flash Point: | 328.6°C |
| Boiling Point: | 619.8°Cat760mmHg |
| Density: | 1.26g/cm3 |
| Refractive index: | 1.654 |
| Biological Activity: | Diacylglycerol (DAG) kinase inhibitor (IC 50 = 2.8 μ M); increases protein kinase C activity. Potentiates thrombin-induced platelet aggregation and induces neutrophil chemotaxis. Inhibits U46619-induced contractions in mouse aorta and porcine coronary artery. |
| Flash Point: | 328.6°C |
| Storage Temperature: | −70°C |
| Color: | pale yellow |
| Safety Data |
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