| Identification |
| Name: | 5,8,11,14-Eicosatetraenamide,N-[(1R)-2-hydroxy-1-methylethyl]-, (5Z,8Z,11Z,14Z)- |
| Synonyms: | 5,8,11,14-Eicosatetraenamide,N-(2-hydroxy-1-methylethyl)-, [R-(all-Z)]-; (R)-Methanandamide; AM 356 |
| CAS: | 157182-49-5 |
| Molecular Formula: | C23H39 N O2 |
| Molecular Weight: | 361.5613 |
| InChI: | InChI=1/C23H39NO2/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-23(26)24-22(2)21-25/h7-8,10-11,13-14,16-17,22,25H,3-6,9,12,15,18-21H2,1-2H3,(H,24,26)/b8-7-,11-10-,14-13-,17-16-/t22-/m1/s1 |
| Molecular Structure: |
![(C23H39NO2) 5,8,11,14-Eicosatetraenamide,N-(2-hydroxy-1-methylethyl)-, [R-(all-Z)]-; (R)-Methanandamide; AM 356](https://img1.guidechem.com/chem/e/dict/17/157182-49-5.jpg) |
| Properties |
| Transport: | UN 1170 3 |
| Density: | 0.935 g/cm3 |
| Refractive index: | 1.501 |
| Water Solubility: | Soluble in ethanol and DMSO |
| Solubility: | Soluble in ethanol and DMSO |
| Appearance: | Colorless oil |
| Biological Activity: | Stable anandamide analog that is a selective agonist for the CB 1 receptor (K i values are 20 and 815 nM for CB 1 and CB 2 receptors respectively). Also displays agonist activity at vanilloid receptors. Also available in water-soluble emulsion ((R)-N-(2-Hydroxy-1-methylethyl)-5Z,8Z,11Z,14Z-eicosatetraenamide ) and as part of the Cannabinoid CB 1 Receptor Tocriset™ . |
| Storage Temperature: | −20°C |
| Safety Data |
| Hazard Symbols |
F: Flammable
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