Identification |
Name: | Ipratropium bromide |
Synonyms: | 8-Azoniabicyclo[3.2.1]octane,3-(3-hydroxy-1-oxo-2-phenylpropoxy)-8-methyl-8-(1-methylethyl)-, bromide,(3-endo,8-syn)- (9CI);8-Isopropylatropinium bromide (6CI,7CI);8-Azoniabicyclo[3.2.1]octane,3-(3-hydroxy-1-oxo-2-phenylpropoxy)-8-methyl-8-(1-methylethyl)-, bromide,(endo,syn)-;Atrovent;N-Isopropylatropinium bromide;N-Isopropylnoratropinium bromomethylate;Sch100;Sch 1000; |
CAS: | 22254-24-6 |
EINECS: | 244-873-8 |
Molecular Formula: | C20H30NO3.Br |
Molecular Weight: | 412.42 |
InChI: | InChI=1/C20H30NO3.BrH/c1-14(2)21(3)16-9-10-17(21)12-18(11-16)24-20(23)19(13-22)15-7-5-4-6-8-15;/h4-8,14,16-19,22H,9-13H2,1-3H3;1H/q+1;/p-1/t16-,17?,18-,19?,21?;/m1./s1 |
Molecular Structure: |
![(C20H30NO3.Br) 8-Azoniabicyclo[3.2.1]octane,3-(3-hydroxy-1-oxo-2-phenylpropoxy)-8-methyl-8-(1-methylethyl)-, bromid...](https://img1.guidechem.com/chem/e/dict/136/22254-24-6.jpg) |
Properties |
Stability: | Stable. Incompatible with strong oxidizing agents. |
Water Solubility: | Freely soluble |
Solubility: | H2O: 10 mg/mL |
Appearance: | powder/white solid |
Specification: |
Ipratropium bromide , its CAS NO. is 22254-24-6, the synonyms are [(1R,5S)-8-Methyl-8-propan-2-yl-8-azoniabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenylpropanoate bromide ; 8-Isopropylnoratropine methobromide ; 3-alpha-Hydroxy-8-isopropyl-1-alpha-H,5-alpha-H-tropanium bromide (+-)-tropate ; N-Isopropylnoratropinium bromomethylate .
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Biological Activity: | Muscarinic antagonist, bronchodilator. N-Isopropyl salt of atropine. |
Storage Temperature: | Keep tightly closed. |
Color: | white |
Usage: |
Ipratropium bromide (CAS NO.22254-24-6) is administered by inhalation for the treatment of obstructive lung diseases.
It is also combined with albuterol (salbutamol) (trade names Combivent and Duoneb, in Italy known as Breva) for the management of chronic obstructive pulmonary disease (COPD) and asthma. It is also combined with fenoterol (trade names Duovent and Berodual N) for the management of asthma.
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Safety Data |
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