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Pyramal maleate (59-33-6)

Identification
Name:Pyramal maleate
Synonyms:1,2-Ethanediamine, N1-[(4-methoxyphenyl)methyl]-N2,N2-dimethyl-N1-2-pyridinyl-, (2Z)-2-butenedioate (1:1);ANTHISAN;histosol;N-(4-Methoxybenzyl)-N',N'-dimethyl-N-(2-pyridinyl)-1,2-ethanediamine (2Z)-2-butenedioate (1:1);N-(4-Methoxybenzyl)-N',N'-dimethyl-N-(pyridin-2-yl)ethane-1,2-diamine (2Z)-but-2-enedioate (1:1);N-(4-methoxybenzyl)-N',N'-dimethyl-N-pyridin-2-ylethane-1,2-diamine (2Z)-but-2-enedioate;N-[(4-Methoxyphenyl)methyl]-N',N'-dimethyl-N-2-pyridinyl-1,2-ethanediamine (2Z)-2-Butenedioate (1:1);N-p-Methoxybenzyl-N',N'-dimethyl-N-a-pyridylethylenediamine Maleate;Thylogen;
CAS:59-33-6
EINECS: 200-422-7
Molecular Formula: C17H23N3O•C4H4O4
Molecular Weight: 401.45618
InChI: InChI=1S/C17H23N3O.C4H4O4/c1-19(2)12-13-20(17-6-4-5-11-18-17)14-15-7-9-16(21-3)10-8-15;5-3(6)1-2-4(7)8/h4-11H,12-14H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
Molecular Structure: (C17H23N3O•C4H4O4) 1,2-Ethanediamine, N1-[(4-methoxyphenyl)methyl]-N2,N2-dimethyl-N1-2-pyridinyl-, (2Z)-2-butenedioate ...
Properties
Melting Point: 100-101ºC
Stability:Stability Combustible. Incompatible with strong oxidizing agents.
Water Solubility:appreciable
Solubility:appreciable
Appearance:white crystalline powder
Specification:

 Pyrilamine maleate ,its CAS NO. is 59-33-6,the synonyms is Mepyramine maleate ; Mepyramine maleate salt ; 2-[(2-Dimethylaminoethyl)(p-methoxybenzyl)amino]pyridine maleate ; Pyrilamine maleate ; Pyrilamine maleate salt ; Pyranisamine maleate ; n-(P-methoxybenzyl)-n',n'-dimethyl-n-2-pyridylethylenediamine maleate ; n-[4-Methoxy-phenyl]methyl-n',n'-dimethyl-n[2-pyridinyl]-1,2-ethanediamine maleate salt .

Report:

Reported in EPA TSCA Inventory.

Biological Activity: Selective inverse agonist for the H 1 receptor. Inhibits histamine induced inositol phosphate (InsP) production (log EC50 = -7.94) and intracellular calcium mobilization. Sequesters G q/11 protein, reducing its availability for other receptors associated with the same signaling pathway.
Storage Temperature: 2-8°C
Usage:Mepyramine maleate is used as bulk pharmaceutical (antihistaminic). Product Data Sheet
Safety Data
Hazard Symbols Xn: Harmful
 

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