| Identification | |
| Name: | Fluticasone propionate |
| Synonyms: | AtemurMite;Cutivate;Cutivate cream;Cyclesonide;Flixonase;FlixonaseNasal Spray;Flixotide;Flixotide Disk;Flixotide Disks;Flixotide Inhaler;Flonase;Flonase Aq;Flovent;Flovent Diskus;Flunase;Fluticasone17-propionate; |
| CAS: | 80474-14-2 |
| Molecular Formula: | C25H31F3O5S |
| Molecular Weight: | 500.57085 |
| InChI: | InChI=1S/C25H31F3O5S/c1-5-20(31)33-25(21(32)34-12-26)13(2)8-15-16-10-18(27)17-9-14(29)6-7-22(17,3)24(16,28)19(30)11-23(15,25)4/h6-7,9,13,15-16,18-19,30H,5,8,10-12H2,1-4H3/t13-,15+,16+,18+,19+,22+,23+,24+,25+/m1/s1 |
| Molecular Structure: |  |
| Properties | |
| Density: | 1.32 g/cm3 |
| Refractive index: | 31 ° (C=1, Dioxane) |
| Appearance: | Crystalline Solid |
| Specification: | Crystalline Solid usageEng:An antiallergic and anti inflammatory Safety Statements:22-24/25 22:Do not breathe dust 24/25:Avoid contact with skin and eyes |
| Biological Activity: | High affinity, selective glucocorticoid receptor agonist (K d = 0.5 nM). Potently stimulates glucocorticoid receptor-mediated transactivation of gene expression and enhances human eosinophil apoptosis (EC 50 = 3.7 nM) in vitro . Inhibits mast cell accumulation in nasal mucosa following topical administration. Lipophilic, clinically-used anti-inflammatory agent with low oral bioavailability. |
| Storage Temperature: | Store in original container in a cool dark place. |
| Color: | white |
| Usage: | An antiallergic and anti inflammatory |
| Safety Data | |
 |
|
