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3,4,5-Piperidinetriol,2-(hydroxymethyl)-1-nonyl-, (2R,3R,4R,5S)- (81117-35-3)

Identification
Name:3,4,5-Piperidinetriol,2-(hydroxymethyl)-1-nonyl-, (2R,3R,4R,5S)-
Synonyms:3,4,5-Piperidinetriol,2-(hydroxymethyl)-1-nonyl-, [2R-(2a,3b,4a,5b)]-; N-Nonyl-1-deoxynojirimycin; N-Nonyldeoxynojirimycin; NNDNJ; Nonyl-DNJ
CAS:81117-35-3
Molecular Formula: C15H31 N O4
Molecular Weight: 0
InChI: InChI=1/C15H31NO4/c1-2-3-4-5-6-7-8-9-16-10-13(18)15(20)14(19)12(16)11-17/h12-15,17-20H,2-11H2,1H3
Molecular Structure: (C15H31NO4) 3,4,5-Piperidinetriol,2-(hydroxymethyl)-1-nonyl-, [2R-(2a,3b,4a,5b)]-; N-Nonyl-1-deoxynojirimycin; N...
Properties
Flash Point: 224.5°C
Boiling Point: 451.7°C at 760 mmHg
Density:1.112g/cm3
Refractive index:1.522
Biological Activity: Glucosidase inhibitor (IC 50 values are 0.42 and 8.4 μ M for acid α -glucosidase and α -1,6-glucosidase respectively). Inhibits liver glycogen breakdown in vivo . Also acts as a chemical chaperone; chaperones β -Glu folding at neutral p.H. allowing the stabilized enzyme to transit from the endoplasmic reticulum to the golgi, enabling proper trafficking to the lysosome.
Flash Point: 224.5°C
Usage:An inhibitor of a-glucosidase 1 as well as being an inhibitor of HIV cytopathicity. A possible therapeutic agent for Gaucher disease.
Safety Data