Identification |
Name: | 3,4,5-Piperidinetriol,2-(hydroxymethyl)-1-nonyl-, (2R,3R,4R,5S)- |
Synonyms: | 3,4,5-Piperidinetriol,2-(hydroxymethyl)-1-nonyl-, [2R-(2a,3b,4a,5b)]-; N-Nonyl-1-deoxynojirimycin; N-Nonyldeoxynojirimycin; NNDNJ; Nonyl-DNJ |
CAS: | 81117-35-3 |
Molecular Formula: | C15H31 N O4 |
Molecular Weight: | 0 |
InChI: | InChI=1/C15H31NO4/c1-2-3-4-5-6-7-8-9-16-10-13(18)15(20)14(19)12(16)11-17/h12-15,17-20H,2-11H2,1H3 |
Molecular Structure: |
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Properties |
Flash Point: | 224.5°C |
Boiling Point: | 451.7°C at 760 mmHg |
Density: | 1.112g/cm3 |
Refractive index: | 1.522 |
Biological Activity: | Glucosidase inhibitor (IC 50 values are 0.42 and 8.4 μ M for acid α -glucosidase and α -1,6-glucosidase respectively). Inhibits liver glycogen breakdown in vivo . Also acts as a chemical chaperone; chaperones β -Glu folding at neutral p.H. allowing the stabilized enzyme to transit from the endoplasmic reticulum to the golgi, enabling proper trafficking to the lysosome. |
Flash Point: | 224.5°C |
Usage: | An inhibitor of a-glucosidase 1 as well as being an inhibitor of HIV cytopathicity. A possible therapeutic agent for Gaucher disease. |
Safety Data |
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